A monthly recap of the latest news about Alzheimer’s and dementia

 

Lilly drug slows Alzheimer’s by 35%, bolstering treatment approach

An experimental Alzheimer’s drug developed by Eli Lilly and Co (LLY.N) slowed cognitive decline by 35% in a late-stage trial, the company said on Wednesday, providing what experts say is the strongest evidence yet that removing sticky amyloid plaques from the brain benefits patients with the fatal disease. Read more here.

 

MIND and Mediterranean diets linked to fewer signs of Alzheimer’s brain pathology

The MIND and Mediterranean diets — both of which are rich in vegetables, fruits, whole grains, olive oil, beans, and fish — are associated with fewer signs of Alzheimer’s disease in the brains of older adults. Read more here.

 

NIH researchers identify large genetic changes that contribute to dementia risk

Discovery provides potential clues for Lewy body and frontotemporal dementias. Read more here. 

 

Less myelin content in the brain linked to faster cognitive decline

People whose brains have less myelin — the fatty tissue that insulates nerve cells — experience steeper declines in cognition over time, according to an NIA study published in Alzheimer’s & Dementia. Read more here.

 

FDA Approves First Drug to Treat Agitation Symptoms Associated with Dementia due to Alzheimer’s Disease

The U.S. Food and Drug Administration is announcing the supplemental approval of Rexulti (brexpiprazole) oral tablets for the treatment of agitation associated with dementia due to Alzheimer’s disease. This is the first FDA-approved treatment option for this indication. Read more here.

 

Mutation Protected Man From Alzheimer’s Disease, Hinting at Treatment

The man should have gotten Alzheimer’s disease in his early 40s — he had a gene mutation that guaranteed it, or so it seemed. Read more here.

 

Study of mouse neurons uncovers novel therapeutic role of removing a genetic variant in the treatment of Alzheimer’s disease

Removing a genetic risk factor from neurons reduces pathological hallmarks of Alzheimer’s disease in mice, according to an NIA-funded study. Read more here.

 

Deep Sleep May Be the Best Defense Against Alzheimer’s

Shakespeare said slumber was ‘the main course in life’s feast.’ Studies suggest is also protects the brain. Read more here. 

 

Insomnia drug may lower levels of Alzheimer’s proteins

Past studies have found links between poor sleep and Alzheimer’s disease. Poor sleep may contribute to dementia risk. The development of cognitive decline and dementia may also disrupt sleep. Read more here.